No., it should not. Installing zsnes:i386 requires i386 versions of several libraries that are incompatible with amd64 programs. For instance, one cannot have both zsnes:i386 and mpd:amd64 installed. I can confirm that this bug is still significant in Oneiric.
No., it should not. Installing zsnes:i386 requires i386 versions of several libraries that are incompatible with amd64 programs. For instance, one cannot have both zsnes:i386 and mpd:amd64 installed. I can confirm that this bug is still significant in Oneiric.