The multimedia keys indeed won't work when NumLock is enabled.
Section "InputDevice" Identifier "Generic Keyboard" Driver "kbd" Option "CoreKeyboard" Option "XkbRules" "xorg" Option "XkbModel" "pc105" Option "XkbLayout" "de" Option "XkbVariant" "nodeadkeys" EndSection
The multimedia keys indeed won't work when NumLock is enabled.
Section "InputDevice"
Identifier "Generic Keyboard"
Driver "kbd"
Option "CoreKeyboard"
Option "XkbRules" "xorg"
Option "XkbModel" "pc105"
Option "XkbLayout" "de"
Option "XkbVariant" "nodeadkeys"
EndSection